腹腔透析患者中与药物有关的问题:一项为期12年的回顾性队列研究
Hui Yin Tay1,2, Farida Islahudin2, Yi Yun Siaw1
1Department of Pharmacy, Hospital Tengku Ampuan Rahimah, Klang, MYS.
Cureus
|October 21, 2024
概括
与药物相关的问题 (DRPs) 在腹透析 (PD) 患者中非常普遍,药物效应不足最常见. 药剂师在识别和解决这些问题方面至关重要,以改善患者的治疗结果.
科学领域:
- 药理学 药理学是指药理学的学科.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床药房 临床药房
背景情况:
- 与药物相关的问题 (DRPs) 在腹透析 (PD) 患者群体中没有得到充分研究.
- 药物药物治疗可以对患者的治疗结果产生负面影响,并增加医疗保健成本.
- 了解PD中的DRP对于优化治疗和患者护理至关重要.
研究的目的:
- 确定PD患者中DRP的患病率,类型和原因.
- 评估干预措施,接受率和DRP管理的结果.
- 在这个人群中识别与DRP相关的因素.
主要方法:
- 2009年1月至2021年11月,对成人PD患者进行的一项单中心回顾性研究.
- 药房药物治疗遵守诊所 (MTAC) 记录的审查.
- 使用欧洲药物护理网络 (PCNE) 药物治疗药物的分类v9.1.1.
主要成果:
- 92.5%的PD患者至少经历过一次DRP.
- 最常见的DRP包括低于最佳的药物效应 (47.8%) 和未经治疗的症状 (25.3%).
- 患者的不遵守是次优效果的主要原因;缺乏对指示条件的处方导致未经治疗的症状. 处方水平的干预最频繁,接受率为83%,DRP的73.2%得到解决. 多药房和MTAC的访问频率预测了DRP的发生.
结论:
- 腹腔透析患者表现出与药物相关问题的高发病率.
- 药剂师在检测,干预和解决DRP方面发挥着重要作用.
- 通过药剂师参与来解决DRP,可以显著改善PD护理中的患者结果.
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