对比增强超声波在预测中风发生的价值:一项前性研究
Yunqian Huang1,2, Chuanjian Chen2, Junni Shi2
1Department of Stroke Center, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu province, China.
Heliyon
|October 21, 2024
概括
与对比度增强的超声波 (CEUS) 检测到 carotid 斑块中的新血管化是中风的重要预测因素. 这种输液模式,显示微泡进入斑块,可以帮助识别高风险患者,以便做出更好的临床决策.
科学领域:
- 血管超声波是指血管超声波.
- 脑血管疾病 脑血管疾病
- 医疗成像医学成像
背景情况:
- 在全球范围内,中风仍然是导致残疾和死亡的主要原因.
- 动脉斑块是缺血性中风的主要危险因素.
- 准确识别易受伤害的动脉斑块对于预防中风至关重要.
研究的目的:
- 为了研究对比增强超声波 (CEUS) 检测到的喉斑块和中风发生的 perfusion 模式之间的关联.
- 确定CEUS是否能够在患有动脉疾病的患者中识别中风的独立预测因子.
主要方法:
- 一项前性观察性研究招募了256名接受动脉超声波的患者.
- 151名患者接受了CEUS,以评估动脉斑块 perfusion 模式.
- 考克斯回归分析用于确定中风发生的独立预测因素.
主要成果:
- 在所有受试者中,最近的症状,中度至重度的动脉狭窄,纤维状盖的化,以及斑块内的斑块性低声区独立预测了中风.
- 在接受CEUS的患者中,中度至严重的动脉狭窄和微泡从其表面进入斑块是中风的独立预测因素.
结论:
- 新血管化 perfusion 模式,其特点是微泡从表面进入斑块内部,是中风发生的独立预测因素.
- 通过CEUS检测斑块新血管化,可以提高对中风风险分层的临床决策.
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