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基于多式成像的COVID-19患者视网膜微血管缺血的谱

Min Zhang¹, Junran Sun¹, Chanchan Wang²

¹Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

|October 21, 2024

概括

COVID-19可以导致视网膜微血管缺血,呈现为棉花斑和偏中心急性中间黄斑病. 多模式成像有助于揭示这些眼部表现的程度和严重程度.

科学领域:

眼科医生眼科眼科
传染性疾病传染性疾病
微循环是一种微循环.

背景情况:

COVID-19 感染与各种系统性并发症有关.
眼部表现,包括视网膜微血管变化,在COVID-19患者中越来越多地报告.
了解这些视网膜变化对于全面的患者管理至关重要.

研究的目的:

描述和评估与COVID-19相关的视网膜微血管缺血中的多式成像发现.
描述COVID-19相关缺血所涉及的特定视网膜层和模式.
评估多式成像在诊断和评估COVID-19相关视网膜病变中的实用性.

主要方法:

从COVID-19患有视网膜微血管缺血症的患者的多模式图像的回顾性审查.
视网膜微血管缺血的定义,如色底图像上的焦点视网膜白化.
排除具有先前存在的视网膜血管封闭或全身视网膜病变的患者.

主要成果:

分析了21名患有COVID-19相关视网膜微血管缺血症的患者的32只眼睛.
常见的发现包括棉羊毛斑 (CWS) 和偏中心急性中间黄斑病 (PAMM),其中59.38%的眼睛显示两者.
患有高血压的患者更有可能出现多重缺血性病变 (P=0.008).

结论:

与COVID-19相关的微血管缺血呈现变化,包括CWS,PAMM和亨尔纤维层高反射性 (ASHH) 的角标志.
多模式 fundus成像有效地可视化所涉及的视网膜层,这些缺血事件的范围和严重程度.
眼睛的发现可能会提供关于COVID-19对系统微循环的影响的见解.

关键词:

亨勒纤维层超反射性的角标志.在 COVID-19 疫情中,棉羊毛斑点的地方偏中心性急性中等黄斑病变视网膜微血管缺血症视网膜微血管缺血症

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