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精神分裂症短期和密集的神经反治疗的认知影响:单一中心试点研究

Fabrizio Turiaco¹, Fiammetta Iannuzzo¹, Giovanni Genovese²

¹Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy.

AIMS neuroscience

|October 21, 2024

概括

神经反训练改善了精神分裂症患者的认知功能. 这种辅助疗法在记忆和注意力方面显著改善,为认知症状管理提供了一种新的策略.

科学领域:

神经科学是一个神经科学.
精神病学是一个精神病学.
认知康复认知康复认知康复

背景情况:

精神分裂症在多达98%的患者中显著影响认知功能.
神经反 (NF) 通过认知过程调节神经网络,可能诱导结构性大脑变化,如增加灰质体积.

研究的目的:

为了评估辅助的阿尔法/甲基NF训练对精神分裂症患者认知缺陷的疗效.
评估一个简短的,密集的NF协议对认知表现和临床症状的影响.

主要方法:

一项为期2周的开放性研究,涉及9名接受非典型抗精神病药物的精神分裂症患者.
每天30分钟的NF课程 (共8个课程),使用alpha/theta训练.
使用ENB2,MMSE和Stroop测试进行认知评估;使用PANSS评估临床症状.

主要成果:

在"故事回忆即时"",故事回忆延迟"",干扰记忆30秒"",时钟测试"子测试中观察到显著改善.
在ENB2总分显示显著改善 (p = 0.007).
在阳性和阴性综合征量表 (PANSS) 分量表或总得分中没有发现显著变化.

结论:

神经反 (NF) 显示出作为精神分裂症认知症状的辅助治疗的希望.
这种密集的NF协议可以增强精神分裂症影响的特定认知领域.
在治疗精神分裂症相关认知障碍的治疗方案中,NF可能是一个有价值的补充.

关键词:

无效性是一种无效性.认知症状认知症状通过神经反,可以获得神经反.精神分裂症是一种精神分裂症.工作记忆工作记忆

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