布罗卢齐祖马布治疗后的隐蔽性视网膜血管炎和硬化症:一个病例报告
Shunpei Onagawa1, Masahiro Miura
1Department of Ophthalmology, Tokyo Medical University, Ibaraki Medical Center, Inashiki, Ibaraki, Japan.
Medicine
|October 21, 2024
概括
对于湿湿的与年龄相关的黄斑退行症的布罗卢齐祖马布治疗可能会导致视网膜血管炎和硬化症. 及时识别和管理对于经历这些布罗卢齐祖马布并发症的患者的积极结果至关重要.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 血管疾病是血管疾病.
背景情况:
- 布罗卢齐祖马布是一种抗VEGF药物,有效治疗新血管与年龄相关的黄斑变性 (nAMD).
- 虽然brolucizumab有效,但与更高的并发症发生率有关,特别是闭塞性视网膜血管炎.
- 本病例报告详细介绍了一位经历了这些不良事件的患者.
研究的目的:
- 报告在nAMD治疗后出现闭塞性视网膜血管炎和随后的硬化症的病例.
- 强调识别和管理布罗卢齐祖马布引起的并发症的重要性.
主要方法:
- 一名67岁的男性患有多性冠状血管病变,接受了静脉内布鲁西祖马布注射.
- 患者在第二次注射后出现了闭塞性视网膜血管炎.
- 皮质类固醇治疗是为了血管炎而开始的,后来是为了硬化症.
主要成果:
- 患者经历了广泛的闭塞性视网膜血管炎与眼内炎症17天后第二次布罗卢齐祖马布注射.
- 血管炎通过皮质类固醇治疗而消失.
- 后来出现了带有眼内炎症的硬化症,这种炎症也通过局部皮质类固醇得到缓解.
结论:
- 布罗卢齐祖马布可以诱导硬化炎,需要及时诊断和管理.
- 长期随访对于在布罗卢齐祖马布治疗后出现闭塞性视网膜血管炎的患者至关重要.
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