同时的甲状腺疾病是否会导致结肩膀的结果更差? 一个系统的审查
Sean Kean Ann Phua1, Rachel Si Ning Loh2, Bryan Yijia Tan3
1Department of Orthopaedic Surgery, Tan Tock Seng Hospital, Singapore.
Journal of shoulder and elbow surgery
|October 21, 2024
概括
甲状腺疾病不会持续恶化结肩的结果,尽管它们已知的关联. 这一系统性审查没有明确证据表明这两种疾病患者的预后较差.
科学领域:
- 整形外科 整形外科 整形外科
- 内分泌学 在内分泌学.
- 系统性审查和元分析
背景情况:
- 结肩膀是一种常见的疾病,会引起疼痛和有限的运动能力,经常与甲状腺疾病有关.
- 同时发生的甲状腺疾病对结肩的预后的影响仍然不清楚.
- 这项研究调查了甲状腺疾病是否会对冷肩的临床结果产生负面影响.
研究的目的:
- 评估是否同时发生的甲状腺疾病导致诊断为肩结的患者的临床结果较差.
- 综合现有关于甲状腺疾病和冷肩部恢复之间的预后关联的证据.
主要方法:
- 系统审查和元分析遵循PRISMA指南,搜索PubMed和Embase.
- 包括在内的人类研究报告的临床结果,为患者的双结肩和甲状腺疾病.
- 使用预测研究工具中的质量和通过GRADE框架的证据质量评估偏差风险.
主要成果:
- 分析了7项涉及超过167,000名受试者的研究.
- 一项研究表明,甲状腺功能低下症的结果有所改善,另一项研究表明,甲状腺功能障碍的结果更差,而五项研究发现没有显著差异.
- GRADE评估显示"非常低"到"低"的质量证据,显示甲状腺疾病和结肩膀结果之间没有一致的预后联系.
结论:
- 虽然结肩膀和甲状腺疾病患病率之间存在相关性,但目前的文献缺乏一致的证据.
- 同时的甲状腺疾病似乎不会使患者在冷的肩膀中更糟糕的临床结果.
- 需要进一步进行高质量的研究来澄清这种关系和潜在的预后影响.
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