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心肌机械功能通过心血管磁共振测量心力衰竭患者的心脏功能

Yufan Gao¹, Boxin Li², Yanhe Ma²

¹Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, China; Department of Radiology, Chest Hospital, Tianjin University, Tianjin 300222, China.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

|October 21, 2024

概括

所有类型的心力衰竭 (HF) 中都存在心肌应变损伤,这为监测疾病进展提供了一个工具. 菌株分析揭示了HFpEF,HFmrEF和HFrEF患者的不同模式.

科学领域:

心脏病学心脏病学
医疗成像医学成像
生物医学工程生物医学工程

背景情况:

心肌应变分析对于评估心脏力学和检测心脏功能障碍至关重要.
心力衰竭 (HF) 包含各种各样的亚型,具有不同的病理生理机制.
了解HF的菌株模式对于诊断和管理至关重要.

研究的目的:

评估不同类型心力衰竭患者心肌应变的模式.
为了比较心肌应变参数,在HF与保留喷射分数 (HFpEF),HF与中等射程喷射分数 (HFmrEF) 和HF与减少喷射分数 (HFrEF) 之间进行.
探索菌株参数与HF严重程度的临床标志物之间的关系.

主要方法:

心脏磁共振成像 (CMR) 功能跟踪被用于测量心肌应变.
包括195名HF患者 (HFpEF,HFmrEF,HFrEF) 和35名对照患者.
还进行了定量组织评估 (原生T1,细胞外体积).

主要成果:

与对照组相比,所有HF组都显示左心室 (LV) 应变和应变率在辐射,周长和纵向方向受损.
LV菌株与LV射出分数和大脑天然尿素水平有显著的相关性.
在HF亚型中观察到LV扭转和隔膜收缩的不同模式;HFpEF显示扭转增加,而HFrEF显示扭转减少.

结论:

心肌应变损伤在HFpEF,HFmrEF和HFrEF中呈现严重程度的范围.
应变分析是监测心缩和腹缩功能障碍在HF患者的进展的一个有价值的工具.
基于CMR的应变评估有助于区分高频类别和理解潜在的机制.

关键词:

在CMR中,CMR是CMR.心脏衰竭是因为心脏衰竭.心肌机械学的心肌机械学压力应变是一种压力.

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