长期Covid:全球卫生问题 - 一项前性,在四大洲进行的队列研究
Ekaterina Pazukhina1, Esteban Garcia-Gallo1, Luis Felipe Reyes2,3
1ISARIC Global Support Centre, Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
BMJ global health
|October 21, 2024
概括
长期的Covid影响全球人口,高收入国家 (HICs) 的流行率更高,但由于支持系统较少,低收入和中等收入国家 (LMICs) 的影响可能更大. 进一步的研究对于公平的COVID-19结果至关重要.
科学领域:
- 全球健康 全球健康
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 长期Covid (COVID-19后的情况) 影响个人在急性COVID-19感染后.
- 目前对长期Covid的大部分研究都集中在高收入国家 (HICs),使全球负担在很大程度上未知.
- 了解不同全球人口中的长期Covid连续病例至关重要.
研究的目的:
- 在全球范围内描述COVID-19的长期症状和影响.
- 为了比较HIC和低收入和中等收入国家 (LMIC) 之间的长期Covid症状的流行率.
主要方法:
- 这是一项在非洲,亚洲,欧洲和南美洲的17个国家进行的前性观察性研究.
- 确诊COVID-19的成年人在出院2至12个月后进行了评估.
- 标准化数据收集评估了发烧,呼吸困难,疲劳等症状,以及对日常活动的影响.
主要成果:
- 该研究包括11,860名参与者,其中56.5%来自HIC和43.5%来自LMIC.
- 在两个评估点上,HICs (69.0-69.7%) 与LMICs (45.3-42.4%) 相比,长期Covid的流行率显著更高.
- 参与HIC的参与者报告说,感觉不完全恢复,疲劳,持续发烧,焦虑/抑郁以及对日常活动的影响更高.
结论:
- 长期Covid在全球范围内表现出类似的症状和功能影响,影响HIC和LMIC.
- 虽然HIC的流行率更高,但由于支持系统有限,LMIC的影响可能更严重.
- 对长期Covid病因和LMICs负担的进一步研究对于开发可访问和有效的干预措施至关重要.
相关概念视频
01:18Factors Affecting Illness
4.2K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
4.2K
01:26Principles of Disease Surveillance
69
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
69
01:20COPD: Pathogenesis and Clinical Features
238
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
238
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
01:05Single Nucleotide Polymorphisms-SNPs
14.1K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
14.1K
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
2.8K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
2.8K