评估与基囊复制后反流复发相关的因素
Hala Al Asadi1, Haythem Najah2, Teagan Marshall1
1Division of Endocrine & Minimally Invasive Surgery, Department of Surgery, Weill Cornell Medical College, New York-Presbyterian Hospital, 525 East 68th Street, K-836, New York, NY, 10065, USA.
Surgical endoscopy
|October 21, 2024
概括
基囊复合后的反复性反流与患者因素无关,但包裹后的低间歇性托皮拉 (HPZ) 比率是显著的风险因素. 需要进行进一步的研究,以建立HPZ指导方针,以确定基金复制结果.
科学领域:
- 胃肠病学 胃肠病学
- 手术创新 在外科创新.
- 医疗器械技术 医疗器械技术
背景情况:
- 基金复制后的逆流复发是一个临床挑战.
- 了解相关的风险因素对于改善患者的治疗结果至关重要.
- 目前对预测复发的因素的知识仍然有限.
研究的目的:
- 为了调查患者和手术期间的因素,与重复的反流在一次性基底复合后.
- 为了确定复发性胃食道逆流性疾病 (GERD) 的预测因素,需要重新干预.
- 探索阻抗平面测量 (EndoFLIPTM) 在评估包裹功能和预测结果中的作用.
主要方法:
- 对137名接受初级基底复制的患者进行了回顾性审查.
- 通过DeMeester分数> 14.7.7定义的反复反流.
- 多变量逻辑回归分析用于风险因素识别.
- 阻抗平面测量分析 (EndoFLIPTM) 间歇性托皮拉津 (HPZ) 测量,如有.
主要成果:
- 12.4%的患者经历了反复的反流;6.5%需要二次手术.
- 两组之间没有发现人口统计学或术前/术后因素的显著差异.
- 包裹后低间歇性托皮拉 (HPZ) 值是反复反流的显著风险因素 (RR 0.15,p=0.01) 并与DeMeester分数相关.
结论:
- 患者的人口统计学 (年龄,性别,BMI,种族) 不能预测复发性反流后的基金复制.
- 低的包装后期托皮拉 (HPZ) 值是反复反流的关键风险因素.
- 需要进行更大规模的研究来验证HPZ的影响,并制定基金复制的临床指南.
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