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基于模型的HbA1c降低SGLT2抑制剂的元分析,使用剂量根据尿液中的葡萄糖分泌量进行调整

Hiromi Sato1, Ayana Ishikawa2, Hideki Yoshioka2,3

  • 1Laboratory of Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuou-ku, Chiba-shi, Chiba, 260-8679, Japan. hiromi-s@chiba-u.jp.

Scientific reports
|October 21, 2024
PubMed
概括

葡萄糖共载体-2 抑制剂 (SGLT2is) 显示出一种统一的剂量反应,用于降低2型糖尿病中的HbA1c,主要是由尿路中的葡萄糖分泌驱动的. 卡纳格利弗洛辛的最大效果比其他SGLT2is.

关键词:
糖尿病 糖尿病 糖尿病基于模型的元分析.药物指标 (Pharmacometrics) 是一个指标.这是一种SGLT2抑制剂.

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