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Updated: Jun 9, 2025

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谷氨酸感应许可证胆固醇合成

Bruna Martins Garcia1, Philipp Melchinger1, Tania Medeiros1

  • 1Max Planck Institute for Biology of Ageing, Cologne, Germany.

The EMBO journal
|October 21, 2024
PubMed
概括

氨基酸谷氨胺激活了产生胆固醇的美瓦酸通路. 谷氨胺缺乏通过阻断SCAP和SREBP2的贩运来破坏胆固醇合成,这是胆固醇生产的关键调节者.

关键词:
胆固醇 胆固醇 胆固醇在HMGCR中,HMGCR是最重要的.在MFN2中,MFN2是MFN2.营养物质感应 营养物质感应在SREBP2中,您可以使用SREBP2.

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