早期手势发育作为自闭症谱系障碍的预测因子,在患ASD的可能性较高的婴儿中
Linru Liu1, QianYing Ye1, Yu Xing1
1Child Development and Behavior Center, Third Affiliated Hospital of SUN YAT-SEN University, No.600 Tianhe Road, Guangzhou, Guangdong, 510630, China.
自闭症谱系障碍 (ASD) 的高概率 (EL) 的婴儿的手势发展轨迹与低概率 (LL) 的婴儿不同. 特定的手势模式,特别是综合手势 (G-M),可以预测ASD的发展.
科学领域:
- 发展心理学是发展心理学.
- 神经发育障碍 神经发育障碍
- 儿科医学 儿科医学 儿科医学
背景情况:
- 在患有自闭症谱系障碍 (ASD) 的儿童的兄弟姐妹中注意到手势困难.
- 早期识别婴儿时期手势发展中的行为指标可能有助于早期诊断ASD.
研究的目的:
- 探索 ASD 的可能性较高 (EL) 的婴儿与低概率 (LL) 的婴儿相比,手势发育轨迹.
- 确定手势发展的预测价值,用于早期检测ASD核心特征.
主要方法:
- 纳入了47名EL婴儿和27名LL婴儿.
- 从9个月到19个月,手势频率,沟通功能和整合被纵向评估.
- 自闭症诊断观察计划 (ADOS) 在18-19个月时进行.
主要成果:
- 与LL婴儿相比,EL婴儿的联合注意力 (JA) 姿态发展速度较慢,在14-18个月之间观察到差异.
- 被诊断为ASD的儿童表现出减少的社交互动手势 (12-13个月) 和综合手势 (G-M:15-16个月;G-E:18-19个月).
- 整体手势频率和G-M整合与ADOS沟通和社交互动得分相关.
结论:
- 在EL和LL婴儿之间,JA手势的发育轨迹不同.
- 综合手势 (G-M) 显示出作为ASD早期预测指标的潜力.
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