训练免疫/天生的免疫记忆的知识映射:二十年研究的见解
Jiacheng He1,2, Hongxia Cui1, Guoqian Jiang3
1College of Environment and Chemistry Engineering, Yanshan University, Qinhuangdao, Hebei, P.R China.
Human vaccines & immunotherapeutics
|October 22, 2024
概括
这项研究分析了20年来训练有素的免疫研究,确定了关键机构和主题,如免疫记忆和疫苗开发. 未来的重点可能是训练有素的基于免疫的疫苗,需要更多的临床研究.
科学领域:
- 免疫学 免疫学 免疫学
- 生物医学研究生物医学研究
背景情况:
- 训练免疫,一种天生的免疫记忆形式,在过去二十年中获得了显著的研究兴趣.
- 了解它的机制和应用对于开发新的治疗策略至关重要.
研究的目的:
- 进行从2004年到2023年训练免疫研究的文献计量分析.
- 识别领先的机构,有影响力的研究人员和新兴研究热点.
- 预测训练免疫研究的未来方向,特别是疫苗开发.
主要方法:
- 采用了知识映射和文献计量技术.
- 在Web of Science核心集合数据库上进行文献搜索.
- 使用VOSViewer,CiteSpace和Bibliometrix软件进行数据分析.
主要成果:
- 拉德布德大学尼姆根,波恩大学和哈佛大学是领先的机构.
- 教授Netea MG是该领域最多产的作者.
- 目前的研究热点包括免疫记忆,表观遗传学,代谢重编程和BCG疫苗应用.
- 培训免疫基础疫苗的开发是一个重要的新兴领域.
结论:
- 训练免疫研究正在迅速发展,重点关注其在疫苗开发方面的潜力.
- 未来的研究应该优先考虑前性临床研究,以验证发现并推进治疗应用.
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