短暂禁欲期对精液参数的影响:系统性审查和元分析
Marco Raditya1, Alice Hari Soejono1, Mario Alfonsus Siswanto1
1Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.
The world journal of men's health
|October 22, 2024
概括
较短的禁欲期 (<2天) 提高精子运动性,减少DNA碎片化,可能提高辅助生殖技术 (ART) 的成功. 寡精症患者可能会在更短的禁欲期内看到精子形态的改善.
科学领域:
- 生殖医学 生殖医学
- 安德罗学与人类学
- 生物统计学 生物统计学
背景情况:
- 辅助生殖技术 (ART) 的结果取决于精液参数.
- 目前世界卫生组织 (WHO) 的指导方针建议禁食2-7天.
- 低于最佳的ART疗效表明需要重新评估戒断期.
研究的目的:
- 为了研究更短的禁欲期 (<2天) 对精液参数的影响.
- 为了确定是否减少禁欲可以改善辅助生殖技术 (ART) 的结果.
主要方法:
- 22项研究的系统综述和元分析.
- 在五个主要数据库 (PubMed,Embase,Scopus等) 进行文献搜索. ) 的情况.
- 使用森林地块和偏差风险评估进行定量分析 (纽卡斯尔-太华尺度).
主要成果:
- 较短的禁欲 (<2天) 显著降低了精液量,精子度和DNA碎片化.
- 总和渐进性精子运动率显著增加.
- 寡精症患者表现出精子形态的改善和DNA碎片化的减少.
结论:
- 较短的禁欲期 (<2天) 可能通过改善精子运动性和DNA完整性来提高ART结果.
- 寡精症患者受益于精子形态的改善和更短的禁欲.
- 研究结果建议修订当前的指导方针,以推更短的ART戒断期.
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