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Updated: Jun 9, 2025

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TBK1通过介导IRF5/IRF4轴参与M-CSF诱导的巨细胞极化

Yuanyuan Li1,2,3, Le Ji4, Chang Liu1,2,3

  • 1Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.

The FEBS journal
|October 22, 2024
PubMed
概括

坦克结合激酶1 (TBK1) 调节了巨细胞的两极分化. 抑制TBK1促进M1类的前炎性巨细胞,影响先天免疫和瘤发育.

关键词:
在IRF5/IRF4轴上这是一个M-CSF.在TBK1中,巨细胞是什么?巨细胞是什么?

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