用口服乳糖做结肠镜肠道制备的新方案:一项前性比较研究
Josué Aliaga Ramos1, Danilo Carvalho2, Vitor N Arantes3
1Department of Gastroenterology, Hospital "José Agurto Tello-Chosica", Gastroenterology Service "Madre Zoraida" Clinic, Digestive Endoscopy Unit of San Pablo Clinic, Lima, Peru.
Clinical endoscopy
|October 22, 2024
概括
与聚乙烯糖醇 (PEG) 相比,基于乳糖的肠道制剂显示出优异的结肠清洁和患者耐受性. 这种新的方法为结肠镜准备提供了更好的患者体验.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 结肠直肠癌查 结肠直肠癌查
背景情况:
- 聚乙烯甘醇 (PEG) 是肠道制备的标准,但大量损害了患者的耐受性.
- 乳糖为结肠镜准备提供了一种新的,可能更耐受的替代品.
研究的目的:
- 为了比较基于乳糖的肠道制剂与PEG的疗效和安全性.
- 为了评估结肠清洁,多体检测和患者体验.
主要方法:
- 前性,非盲目的,比较性研究.
- 111名患者接受了PEG,111名患者接受了乳糖.
- 评估结果:波士顿肠道准备分数,多/腺瘤检测率,耐受性,副作用.
主要成果:
- 准备不足率:8.1% (PEG) 与1.8% (乳糖) (p=0.030) 相比.
- 平均波士顿肠道准备分数:7.34±1.17 (PEG) 与8.36±1.09 (乳糖) 相比 (p<0.001).
- 总体体验令人满意:27.9% (PEG) 与62.2% (乳糖) (p<0.001) 相比.
结论:
- 基于乳糖的肠道制剂在结肠清洁方面优于PEG.
- 乳糖可显著改善腺瘤检测率,耐受性和患者体验.
- 口服乳糖为结肠镜准备提供了更有效,更为患者友好的替代品.
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