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通过HDX-MS在血清中直接映射多克隆性皮质

Clint Vorauer1, Camila Boniche-Alfaro2,3, Taylor Murphree1

  • 1Department of Medicinal Chemistry, University of Washington, Seattle, Washington 98195, United States.

Analytical chemistry
|October 22, 2024
PubMed
概括

研究人员开发了一种使用固定抗原和/交换与质谱学 (HDX-MS) 绘制抗体结合位点在抗原上的新方法. 这种技术在复杂的血清环境中揭示了详细的表位图景.

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