过敏性鼻炎与注意力缺陷多动障碍之间的关系:系统性审查和元分析
Qian Wang1,2, Ruikun Wang3, Mengyao Li1
1Department of Otolaryngology-Head and Neck Surgery, Capital Institute of Pediatrics, Beijing, China.
PeerJ
|October 22, 2024
概括
这一元分析证实了过敏性鼻炎 (AR) 与儿童注意力缺陷多动症障碍 (ADHD) 之间的显著联系. AR可能会增加ADHD风险,而ADHD可能会增加AR风险.
科学领域:
- 儿科健康 儿科健康
- 神经科学是一个神经科学.
- 免疫学 免疫学 免疫学
背景情况:
- 过敏性鼻炎 (AR) 和注意力缺陷多动障碍 (ADHD) 之间的关系正在争论中,在研究中发现了相互矛盾的结果.
- 之前的研究对这两种疾病之间确定的关联产生了不确定的结果.
研究的目的:
- 进行全面的元分析,探索过敏性鼻炎和ADHD之间的相关性.
- 综合现有证据,以澄清儿科人口中AR和ADHD之间的关系.
主要方法:
- 在多个数据库中进行了系统的文献搜索,直到2023年.
- 使用R 4.2.2进行了元分析,计算了聚合赔率比率和置信区间.
- 进行了子组和灵敏度分析,以评估发现的异质性和稳定性.
主要成果:
- 包含530,360名参与者的12项研究被纳入了元分析.
- 在ADHD和儿童AR存在之间发现了显著的相关性.
- 患有AR的儿童也与ADHD的发生有显著的相关性.
结论:
- 在儿童和青少年中,过敏性鼻炎和ADHD之间存在实质性的相关性.
- 过敏性鼻炎可能是发展ADHD的危险因素.
- ADHD可能会增加患过敏性鼻炎的可能性.
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