布鲁塞拉菌种的血清流行率 在约旦的牲畜-人界面
Ehab A Abu-Basha1, Zuhair Bani Ismail1, Lea Widemann2
1Jordan University of Science and Technology, Irbid, Jordan.
One health (Amsterdam, Netherlands)
|October 22, 2024
概括
牛病在约旦很普遍,特别是在那些接触牲畜的人群中. 控制动物的疾病对于预防人类感染和减少整体负担至关重要.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 牛病是中东地区的特有动物传染病,但约旦的流行和传播数据有限.
- 现有的知识差距阻碍了该地区对人类和牲畜菌病的有效控制策略.
研究的目的:
- 在约旦调查人类和牲畜中血清病原病的流行率.
- 为了确定人类血病的发病率,并确定与感染相关的风险因素.
主要方法:
- 这是一项纵向研究,涉及约旦五个地点的500名人类参与者 (暴露或未暴露于牲畜) 和700只牲畜.
- 血液样本在基线收集,并在1.5年后进行布鲁塞拉菌种类检测. 使用孟加拉测试 (RBT) 和补体固定测试 (CFT) 的抗体.
主要成果:
- 总体而言,人类血清病菌病发病率为3.4%,在牲畜暴露的个体 (6.1%) 与未暴露的个体 (0.8%) 相比显著更高.
- 人类百菌病发病率为每10万人/年924例,仅限于牲畜暴露组.
- 畜牧类牛菌病血清流行率从基线的5.4%降至随访时的2.6%,在大多数物种和地点检测到.
结论:
- 牛病在约旦造成了严重的健康负担,而与牲畜的职业接触是人类感染的主要风险因素.
- 在牲畜群体中实施强有力的疾病控制措施至关重要,以减轻布鲁塞洛斯感染人类的风险.
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