肥胖和胎盘增殖谱的风险:一个元分析
Ensiyeh Jenabi1, Roya Najafi-Vosough2, Arshia Nazari3
1Mother and Child Care Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Open medicine (Warsaw, Poland)
|October 22, 2024
概括
肥胖可能与更高的胎盘增殖谱 (PAS) 风险有关,但当考虑混因素时,这种关联并不重要. 需要进一步的研究来证实肥胖和PAS之间的关系.
科学领域:
- 产科和妇科 产科和妇科
- 生殖健康 生殖健康
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 肥胖和胎盘增殖谱 (PAS) 之间的关系仍在争论中,一些研究表明存在关联,而另一些研究发现没有.
- 了解这种联系对于改善孕产妇健康结果至关重要.
研究的目的:
- 进行一项元分析,研究肥胖与患有胎盘增殖谱 (PAS) 的风险之间的关联.
主要方法:
- 在主要数据库 (PubMed,科学网,谷歌学者,Scopus) 进行了系统的文献搜索,截至2024年3月30日.
- 在元分析中使用了随机效应模型,使用纽卡斯尔-太华尺度评估研究质量.
- 使用Stata软件确定统计显著性,p值值为<0.05.
主要成果:
- 原始分析表明,肥胖和PAS风险之间存在显著的关联 (OR 1.51,95% CI: 1.19-1.82).
- 然而,经过对混变量进行调整后,肥胖和PAS风险之间的关联在统计上并不显著 (OR 1.25,95%CI:0.45-2.05).
结论:
- 肥胖可能与增加PAS风险有关,特别是在未经调整的分析中.
- 目前的证据表明,需要进行前性队列研究,对混因素进行强有力的控制,以澄清肥胖-PAS关系.
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