使用DPPH扫除试验的希夫基联体的抗氧化活性:更新的审查
Md Sohel Rana1, Noor Mohammad Azbar Rayhan1, Md Shahadat Hossain Emon1
1Department of Chemistry, University of Rajshahi Rajshahi-6205 Bangladesh.
RSC advances
|October 22, 2024
概括
希夫基联体通过清除自由基显示出有前途的抗氧化活性. 结构修改和溶剂选择显著影响它们的有效性,突出了它们作为合成抗氧化剂的潜力.
科学领域:
- 有机化学 有机化学
- 药用化学 医学化学
- 生物化学 生物化学
背景情况:
- 从氨基和碳基中衍生出的希夫基被探索其抗氧化性质.
- 它们通过原子转移 (HAT) 和单电子转移 (SET) 清除DPPH基.
研究的目的:
- 审查希夫基联体的设计,合成和抗氧化活性.
- 为了将结构特征与DPPH激素清除功效相关联.
主要方法:
- 关于希夫基联结体及其抗氧化活性研究的文献综述.
- 分析结构-活性关系,包括替代剂效应和溶剂影响.
主要成果:
- 环上的电子捐赠组增强了抗氧化活性.
- 促进质子/电子捐赠的溶剂增加了激素清除功效.
- 一些希夫基具有比标准抗氧化剂更高的活性.
结论:
- 希夫基联体是有效的合成抗氧化剂来源.
- 建议进行进一步的体外和体内研究,以充分阐明它们的潜力.
- 对希夫基抗氧化剂的研究提供了广泛的应用可能性.
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