在患有初级甲状腺功能低下症的患者中评估睡眠异常的谱
Himamshu Acharya1, Sanjana Jayaraj Mangala1, Pramila Kalra1
1Endocrinology and Metabolism, MS Ramaiah Medical College, Bengaluru, IND.
Cureus
|October 22, 2024
概括
睡眠功能障碍在患有甲状腺功能低下症的患者中很常见. 睡眠问题的严重程度与甲状腺刺激激素 (TSH) 水平没有相关性,这表明甲状腺功能本身并不决定睡眠质量.
科学领域:
- 内分泌学 在内分泌学.
- 睡眠医学 睡眠医学
- 内部医学 内部医学
背景情况:
- 初级甲状腺功能低下症是一种普遍存在的内分泌疾病,具有广泛的全身影响.
- 甲状腺功能障碍与睡眠质量之间的关系尚未得到充分证实.
- 睡眠障碍可能不是甲状腺功能障碍的主要症状,需要进一步调查.
研究的目的:
- 在被诊断为初级甲状腺功能低下症的患者中评估睡眠功能障碍.
- 用验证的问卷来对睡眠障碍进行全面的评估.
- 探索甲状腺功能障碍与睡眠质量之间的相关性.
主要方法:
- 一项涉及81名明显或亚临床原发性甲状腺功能低下症的参与者的横截面研究.
- 参与者使用验证的问卷进行评估,以测量睡眠障碍.
- 纳入标准包括从未服用过药物的患者或甲状腺刺激激素 (TSH) 水平高于4.5μIU/L的患者.
主要成果:
- 研究人口主要为女性 (79%).
- 睡眠不良的人的患病率在亚临床下为66.7%,在明显的甲状腺功能低下症中为60.8%.
- 睡眠呼吸暂停发生在26.7% (亚临床) 和27.5% (开放) 的参与者中,独立于TSH水平.
结论:
- 睡眠功能障碍在明显和亚临床初级甲状腺功能低下症中非常普遍.
- 睡眠障碍的程度与甲状腺功能障碍的严重程度 (TSH水平) 并没有直接相关.
- 这些发现强调了评估甲状腺功能低下患者睡眠的重要性.
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