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Updated: Jun 9, 2025

Enhancing the Engraftment of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes via a Transient Inhibition of Rho Kinase Activity
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胎儿非压缩性心肌病的形态,电生理和分子变化是由ROCK信号的破坏引起的

David Sedmera1,2, Veronika Olejnickova1, Barbora Sankova1

  • 1Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czechia.

Frontiers in cell and developmental biology
|October 22, 2024
PubMed
概括

发育中的心脏中异常的Rho 激酶 (ROCK) 信号会导致暂时的左心室非紧缩. 这种小鼠模型显示了自我纠正,但突出了不同的心室重塑潜力,并将肌细胞增殖与心脏结构和功能联系起来.

关键词:
摇滚 摇滚 摇滚 摇滚心肌细胞的增殖,心肌细胞的增殖.压缩 压缩是一种压缩.导电传导 导电传导 导电传导鼠标胚胎的心脏 鼠标胚胎的心脏肌肉心脏的轨道管 (trabeculae) 在心脏中形成.腹腔壁壁上的心室.

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