对SOS1抑制剂 (2022年至今) 的最新专利审查

Guizhen Zhou1,2, Chuan Zhou3, Xinyi Ma1,4

  • 1Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

概括

新的专利显示SOS1抑制剂针对KRAS驱动的瘤. 虽然有希望,但这些SOS1抑制剂在临床疗效,安全性和药理动力学方面面临挑战,需要进一步开发.

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