毒素注射的超声波可视化:确定临床相关性,以优化性管理结果
Kristen A Harris1, Stacey Jou1, Lora Kasselman2,3
1Physical Medicine and Rehabilitation, Hackensack Meridian Health/JFK Johnson Rehabilitation Institute, Edison, New Jersey, USA.
PM & R : the journal of injury, function, and rehabilitation
|October 22, 2024
概括
用超声波引导的肉毒素注射治疗性可能会在目标肌肉外泄漏,特别是在有纤维脂肪肌肉变化的情况下. 这一发现有助于临床医生优化注射技术,并尽量减少不必要的副作用,如软弱.
科学领域:
- 神经学 神经学
- 肌肉骨医学 肌肉骨医学
- 医疗成像医学成像
背景情况:
- 毒素注射是对的标准治疗方法.
- 潜在的并发症包括由于毒素传播而导致的意外肌肉衰弱.
- 超声波可视化可以识别毒素泄漏,但临床因素未得到充分研究.
研究的目的:
- 在超声波引导的性注射过程中识别注射肉毒素泄漏.
- 将泄漏与肌肉大小,纤维脂肪变化和注射史等临床因素联系起来.
主要方法:
- 在一个学术医疗中心进行前性观察研究.
- 54名患有手腕曲器的患者接受了abotulinumtoxinA注射.
- 超声波录像记录和审查注射物泄漏;与肌肉直径,注射物体积和先前注射相关.
主要成果:
- 在18.5%的注射中观察到注射器泄漏.
- 更高的修改赫克马特尺度得分与泄漏的可能性增加有关.
- 在泄漏和注射体积或肌肉直径之间没有发现显著的关联.
结论:
- 肌肉外的肉毒毒素注射泄漏与纤维脂肪肌肉变化有关.
- 超声波对于可视化毒素传播非常有价值.
- 进一步的研究可能会改进注射策略,以防止泄漏.
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