相关实验视频

Updated: Jun 9, 2025

[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst

[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst

Published on: May 21, 2019

通过比斯穆特光催化剂激活和C-C合化

Mauro Mato¹, Alexios Stamoulis¹, Paolo Cleto Bruzzese²

¹Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470, Mülheim an der Ruhr, Germany.

Angewandte Chemie (International ed. in English)

|October 22, 2024

概括

这项研究引入了一种新的 - 氧化氧化催化方法,用于形成碳 - 碳键. 该过程利用光催化技术将化与醇结合起来,从而使C-H功能化产生C-sp2-C-sp2链接.

科学领域:

有机金属化学有机金属化学
光催化作用的光催化
合成有机化学合成有机化学

背景情况:

在有机合成中,碳-碳键的形成至关重要.
通过C-H功能化合烯化物是一个重要的合成挑战.
乙氧化还原催化是一个新兴领域,有可能产生新的转变.

研究的目的:

开发一种化学选择性方法,用于使用比斯光催化剂形成C(sp2) -C(sp2) 键.
通过C-H功能化实现 (异质) 酸与醇衍生物的合.
阐明双氧化还原状态依赖的双氧化复合物的光化学激活机制.

主要方法:

化学选择性比斯穆特-光催化合反应.
使用 (异质) 酸和醇衍生物作为基质.
研究MLCT和LLCT过程在催化循环中的作用.

主要成果:

通过C-H功能化成功形成C-sp2-C-sp2链接.
展示了一种独特的甲催化合的化与 pyrroles.
双重光化学激活机制的解,其中涉及Bi (I) 和Bi (III) 中介物.

结论:

开发的比斯光催化方法为CC键形成提供了一条新的途径.
这项研究突出了双氧化还原状态依赖的双氧化复合物的光化学激活.
这项工作扩大了有机合成中氧化还原催化剂的范围.

关键词:

阿里化物激活激活比斯穆特催化剂的催化作用交叉合反应的交叉合反应光催化作用的光催化作用激进催化剂是激进的催化剂

更多相关视频

Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes

Chemoselective Preparation of 1-Iodoalkynes, 1,2-Diiodoalkenes, and 1,1,2-Triiodoalkenes Based on the Oxidative Iodination of Terminal Alkynes

Published on: September 12, 2018

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-phosphinetriyltripiperidine]}palladium Under Mild Reaction Conditions

Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-phosphinetriyltripiperidine]}palladium Under Mild Reaction Conditions

Published on: March 20, 2014

相关概念视频

Cycloaddition Reactions: MO Requirements for Photochemical Activation

Cycloaddition Reactions: MO Requirements for Photochemical Activation

Some cycloaddition reactions are activated by heat, while others are initiated by light. For example, a [2 + 2] cycloaddition between two ethylene molecules occurs only in the presence of light. It is photochemically allowed but thermally forbidden.

Electrophilic Aromatic Substitution: Fluorination and Iodination of Benzene

Electrophilic Aromatic Substitution: Fluorination and Iodination of Benzene

Bromination and chlorination of aromatic rings by electrophilic aromatic substitution reactions are easily achieved, but fluorination and iodination are difficult to achieve. Fluorine is so reactive that its reaction with benzene is difficult to control, resulting in poor yields of monofluoroaromatic products. To address this, Selectfluor reagent is used as a fluorine source in which a fluorine atom is bonded to a positively charged nitrogen.

Radical Substitution: Hydrogenolysis of Alkyl Halides with Tributyltin Hydride

Radical Substitution: Hydrogenolysis of Alkyl Halides with Tributyltin Hydride

Radical substitution reactions can be used to remove functional groups from molecules. The hydrogenolysis of alkyl halides is one such reaction, where the weak Sn–H bond in tributyltin hydride reacts with alkyl halides to form alkanes. Here, the reagent Bu3SnH yields tributyltin halide as a byproduct.
The bonds formed in this reaction are stronger than the bonds broken, making it energetically favorable. The reaction follows a radical chain mechanism similar to radical halogenation...

Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation

Reduction of Alkynes to cis-Alkenes: Catalytic Hydrogenation

Introduction
Like alkenes, alkynes can be reduced to alkanes in the presence of transition metal catalysts such as Pt, Pd, or Ni. The reaction involves two sequential syn additions of hydrogen via a cis-alkene intermediate.

Photochemical Electrocyclic Reactions: Stereochemistry

Photochemical Electrocyclic Reactions: Stereochemistry

The absorption of UV–visible light by conjugated systems causes the promotion of an electron from the ground state to the excited state. Consequently, photochemical electrocyclic reactions proceed via the excited-state HOMO rather than the ground-state HOMO. Since the ground- and excited-state HOMOs have different symmetries, the stereochemical outcome of electrocyclic reactions depends on the mode of activation; i.e., thermal or photochemical.
Selection Rules: Photochemical Activation

Aryldiazonium Salts to Azo Dyes: Diazo Coupling

Aryldiazonium Salts to Azo Dyes: Diazo Coupling

The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the...