对于食道和食道胃结癌的转化手术
Yoshiaki Shoji1, Kohei Kanamori1, Kazuo Koyanagi2
1Department of Gastroenterological Surgery, Tokai University School of Medicine, 143, Shimokasuya, Isehara-City, Kanagawa, 259-1193, Japan.
International journal of clinical oncology
|October 22, 2024
概括
在初始治疗后的转换手术为无法切除的食道和食道胃结癌提供了潜在的治疗方法. 需要进一步的研究来澄清这种方法的安全性和有效性,以改善患者的预后.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 胃肠道瘤学 胃肠道瘤学
背景情况:
- 化疗,辐射,向治疗和免疫检查点抑制剂免疫治疗 (ICI) 的进展改善了最初无法切除的食道和食道胃结癌的结果.
- 在这种患者群体中,旨在治疗新辅助治疗后治愈的转化手术越来越多地被使用.
研究的目的:
- 审查目前关于转换手术对于最初无法切除的食道和食道胃结癌的安全性和有效性的证据.
- 探索多学科治疗的作用,包括转换手术,作为这些晚期癌症的新策略.
主要方法:
- 对调查食道和食道胃结癌转换手术的研究进行文献综述.
- 对各种治疗线路后转换手术的生存结果,安全性和实用性的数据进行分析.
主要成果:
- 几项研究报告了转换手术后R0切除后令人鼓舞的生存结果.
- 关于转换手术的实用性和安全性的关键方面需要进一步澄清.
结论:
- 转换手术作为多学科方法的一部分,可能为最初无法切除的食道和食道胃结癌提供治疗选择.
- 这一策略有可能改善以前无法治疗的晚期胃肠道癌症患者的预后.
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