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Updated: Jun 9, 2025

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
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Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods

Published on: July 17, 2019

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eIF4F控制了黑色素瘤中具有BRAF和NRAS突变的ERK MAPK信号

Barbora Valcikova1,2, Natalia Vadovicova1,2, Karolina Smolkova1,2

  • 1Department of Biology, Faculty of Medicine, Masaryk University, Brno 62500, Czech Republic.

Proceedings of the National Academy of Sciences of the United States of America
|October 22, 2024
PubMed
概括

eIF4F复合体在黑色素瘤中负面调节MAPK通路. 抑制eIF4F会破坏这种反,导致ERK过度激活,这对于了解黑色素瘤的治疗耐药性至关重要.

关键词:
在DUSP6中,我们可以使用DUSP6.埃尔克·埃尔克是什么意思这就是MAP激酶.在 eIF4F 中.黑色素瘤是一种黑色素瘤.

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