Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

170
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
170
Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

2.3K
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep...
2.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Generalizable structure-function covariation predictive of antidepressant response revealed by target-oriented multimodal fusion.

Nature. Mental health·2026
Same author

A practical framework for discussing sudden unexpected death in epilepsy with patients and families: Resolving the communication gap.

Epilepsia·2026
Same author

Factors associated with rapid pediatric acute seizure emergency treatment: Quality Improvement in Time to Treat Status Epilepticus baseline cohort.

Epilepsia·2026
Same author

Characterizing Onset Limit and Surgical Outcome Factors in Type II Focal Cortical Dysplasia-Related Epilepsy.

Neurology. Clinical practice·2026
Same author

Perceptual-phase eye-tracking during figure copying is associated with amyloid-β PET positivity in mild cognitive impairment.

Journal of Alzheimer's disease : JAD·2026
Same author

Thalamo-Lesional Connectivity Signatures of Bilateral Tonic-Clonic Seizures in Focal Cortical Dysplasia-Related Epilepsy.

Annals of clinical and translational neurology·2026

相关实验视频

Updated: Jun 9, 2025

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording
14:27

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Published on: August 11, 2019

12.4K

纵向海马轴在大型皮质系统中,是基础发展和情节性记忆的基础.

Hua Xie1,2, Venkata Sita Priyanka Illapani1, Lauren T Reppert1

  • 1Center for Neuroscience Research, Children's National Research Institute, Children's National Hospital, Washington, D.C. 20010.

Proceedings of the National Academy of Sciences of the United States of America
|October 22, 2024
PubMed
概括

海马体在其轴线上表现出功能专业化,连接到不同的大脑路径. 这种组织随着时间的推移而发展,对情节性记忆至关重要.

关键词:
发展发展发展发展发展.这是一种情节性记忆 (episodic memory).功能连接性的功能连接性梯度梯度是指一个梯度.在海马体内,海马体

更多相关视频

Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice
09:34

Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice

Published on: June 19, 2019

15.9K
Horizontal Hippocampal Slices of the Mouse Brain
08:59

Horizontal Hippocampal Slices of the Mouse Brain

Published on: September 22, 2020

17.9K

相关实验视频

Last Updated: Jun 9, 2025

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording
14:27

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Published on: August 11, 2019

12.4K
Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice
09:34

Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice

Published on: June 19, 2019

15.9K
Horizontal Hippocampal Slices of the Mouse Brain
08:59

Horizontal Hippocampal Slices of the Mouse Brain

Published on: September 22, 2020

17.9K

科学领域:

  • 神经科学是一个神经科学.
  • 认知神经科学 认知神经科学
  • 发育神经科学的发展神经科学.

背景情况:

  • 海马体在其纵向轴上表现出功能专业化.
  • 了解它与皮质系统的相互作用是发展和认知的关键.

研究的目的:

  • 绘制海马体功能连接 (海马体梯度) 的地形组织及其在发育的大脑中的皮质相互作用.
  • 研究海马梯度及其全脑连接的发育变化.
  • 探索海马-皮质相互作用在情节性记忆中的作用.

主要方法:

  • 在两个大型静止状态功能性MRI数据集上使用连带图谱绘制技术.
  • 量化了海马梯度及其在大规模皮质大脑系统中的整合.
  • 采用表型预测建模来评估海马体在情节性记忆网络中的整合.

主要成果:

  • 揭示了海马体的功能层次结构,前海马体与前 (AT) 路径相连,后海马体与后中间 (PM) 路径相连.
  • 在发育过程中沿海马轴观察到功能专业化的增加.
  • 检测到整个大脑连接的发育转移从后部到前部海马.
  • 识别了PM/AT系统中的关键节点,这些节点对于情节性记忆至关重要.

结论:

  • 海马梯度及其皮质相互作用对大脑发育至关重要.
  • 这种组织支持情节性记忆的神经基础.
  • 海马连接的发育变化完善了它在认知功能中的作用.