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Updated: Jun 9, 2025

Polysome Profiling in Leishmania, Human Cells and Mouse Testis
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Published on: April 8, 2018

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AMBRA1控制了T淋巴细胞中免疫特异性基因的翻译

Simone Gottlieb1, Wanjing Shang2, Deji Ye3

  • 1Molecular Development of the Immune System Section, Laboratory of Immune System Biology, and Clinical Genomics Program, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20814.

Proceedings of the National Academy of Sciences of the United States of America
|October 22, 2024
PubMed
概括

AMBRA1通过控制mRNA翻译和核糖体功能来调节T细胞死亡. 这种蛋白质对于平衡T细胞受体信号与细胞周期进展和细胞死亡途径至关重要.

关键词:
艾姆布拉 (AMBRA) 是一个在 FAS 信号通道上.在T细胞激活过程中,死亡的T细胞死亡.蛋白质翻译是蛋白质的翻译.

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