相关实验视频

Updated: Jun 23, 2026

Shape Memory Polymers for Active Cell Culture

Shape Memory Polymers for Active Cell Culture

Published on: July 4, 2011

热可编程3D形状记忆聚合物基设备的设计,适用于内动脉瘤的内血管治疗

Rakesh Das¹, Tanner L Cabaniss², Sergio A Pineda-Castillo³

¹Department of Bioengineering, University of California Riverside, Riverside, CA, USA.

Journal of the mechanical behavior of biomedical materials

|October 22, 2024

概括

这项研究引入了一种3D打印的,针对患者的形状记忆聚合物 (SMP) 装置,涂有多聚烯 (PPy),用于治疗内动脉瘤 (ICAs). PPy涂层使得有效的朱尔加热可用于部署,有望改善长期动脉瘤封闭.

科学领域:

生物材料工程生物材料工程
医疗器械开发医疗器械开发
聚合物科学聚合物科学

背景情况:

内动脉瘤 (ICAs) 带来了重大风险,目前的内血管卷积治疗面临着不完全封闭和再通道化等挑战.
形状记忆聚合物 (SMP) 为患者特定设备提供了潜在的潜力,以改善治疗结果,而不是传统的卷轴.

研究的目的:

开发和描述一种新的,高度多孔的,针对患者的SMP栓塞装置,用于增强内动脉瘤封闭.
引入聚烯 (PPy) 涂层,以方便通过朱尔加热部署设备,并提高长期疗效.

主要方法:

使用3D打印制造一个多孔的,针对患者的SMP栓塞装置.
应用均的聚烯 (PPy) 涂层,以提高焦耳加热的电导率.
使用脉冲宽度调制电路用于诱导朱尔加热的形状恢复特性.

主要成果:

PPy涂层成功地提高了SMP材料的电和热导电性,对其玻璃过渡温度的影响最小.
参数研究确定了催化剂度和聚合时间的最佳条件,以实现ICA治疗的理想形状恢复.
开发的设备证明了通过焦勒加热诱导的形状恢复来有效地堵塞动脉瘤的潜力.

结论:

为SMP栓塞器件开发了一种有前途的PPy涂层,可实现部署高效的朱尔加热.
这项技术为未来的无线圈,个性化的SMP设备铺平了道路,用于长期和完整的动脉瘤闭塞.
这些发现支持对内动脉瘤进行内血管治疗的进步,以提高疗效和耐用性.

关键词:

大脑动脉瘤的发生导电性聚合物是一种导电性聚合物.血管内栓塞血管内栓塞血管内栓塞血管内栓塞焦力加热是使用焦力加热的.

更多相关视频

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

4D Printed Bifurcated Stents with Kirigami-Inspired Structures

4D Printed Bifurcated Stents with Kirigami-Inspired Structures

Published on: July 25, 2019

相关概念视频

Modified-Release Drug Delivery Systems: Rate-Programmed II

Modified-Release Drug Delivery Systems: Rate-Programmed II

Rate-programmed drug delivery systems release drugs in a controlled manner to maintain therapeutic levels. Three main designs include reservoir, matrix, and hybrid systems.Reservoir systems consist of a drug core enclosed within a membrane that controls drug release. In non-swelling reservoir systems, polymers like ethyl cellulose or polymethacrylates are used. These do not hydrate in aqueous media and control release through membrane thickness, porosity, or insolubility. This type includes...

Aneurysm III: Interprofessional Care

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...