在体力炼期间患有慢性呼吸系统疾病的成年人中使用高流量鼻:系统性审查和元分析
Eduardo Moya-Gallardo1,2,3, Jeniffer Fajardo-Gutiérrez2, Karol Acevedo2,4
1CardioREspirAtory Research Laboratory (CREAR Lab), Departamento de Kinesiología, Escuela de Ciencias de la Salud, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile eemoya@uc.cl.
高流量鼻腔管 (HFNC) 治疗可以改善慢性呼吸系统疾病 (CRD) 患者在肺部康复期间的运动时间. 这种疗法显示出增强功能性运动能力和CRD患者的二次结果的潜力.
科学领域:
- 肺部医学 肺部医学
- 呼吸系统疗法 呼吸系统疗法
- 临床运动生理学 临床运动生理学
背景情况:
- 慢性呼吸道疾病 (CRDs) 影响全球数以百万计的人,导致呼吸障碍和疲劳等衰弱症状.
- 肺部康复 (PR) 计划对于改善CRD患者的运动能力和生活质量至关重要.
- 高流量鼻腔管 (HFNC) 治疗是运动期间的潜在辅助治疗方法,但其在CRD人群中的有效性需要澄清.
研究的目的:
- 系统地审查CRD患者在运动期间HFNC的影响.
- 评估HFNC对功能性运动能力和CRD患者接受PR的二次结果的影响.
主要方法:
- 随机对照试验的系统审查和元分析,比较HFNC与成人CRD患者在运动期间的标准护理.
- 从创建到2023年4月,搜索了八个数据库,由两位作者进行独立选择和数据提取.
- 采用GRADE方法来确定证据的确定性和随机效应模型来进行数据聚合.
主要成果:
- 包括17项涉及570名患者的研究 (n=8406).
- 在多次训练 (WMD=160.58s) 和单次训练 (WMD=72.10s) 之后,HFNC显著增加了炼时间.
- 在HFNC中,在生活质量,呼吸障碍和坚持等次要结果中,有很小的改善潜力.
结论:
- 有证据表明,HFNC可以在运动训练期间提高CRD患者的功能性运动能力.
- 高钢铁公司可能会对二次结果产生积极影响,因此需要进一步研究其在PR中的作用.
- 继续调查是合理的,以充分阐明HFNC在CRD管理中的优势.
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