广东慢性病患者的体力活动元素和不良结果 (PEAKING) 项目:前性队列研究协议
Changyuan Yang1,2, Ruolan Duan1, Zhenhua Yang1
1State Key Laboratory of Traditional Chinese Medicine Syndrome, Chinese Medicine Guangdong Laboratory, Guangdong Provincial Key Laboratory of Chinese Medicine for Prevention and Treatment of Refractory Chronic Diseases, Big Data Research Center of Chinese Medicine, Department of Nephrology, the Second Clinical College of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
BMJ open
|October 22, 2024
概括
在非透析慢性病 (ND-CKD) 患者中,身体不活动是常见的. 这项研究使用加速度计来评估身体活动 (PA) 和其与ND-CKD患者死亡率的联系.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 公共卫生 公共卫生
- 运动生理学 运动生理学
背景情况:
- 在慢性病 (CKD) 患者中,身体不活动很普遍,与不良结果有关.
- 以前的研究主要使用问卷,并专注于透析患者.
- 需要了解非透析CKD (ND-CKD) 患者的体力活动 (PA).
研究的目的:
- 调查中国非透析CKD (ND-CKD) 患者的体力活动 (PA) 水平和类型.
- 检查PA元素与不良结果之间的关联,包括全因死亡率.
- 为了比较加速度计衍生PA与问卷衍生PA.
主要方法:
- 在中国广东,对374名ND-CKD患者进行前性队列研究.
- 使用ActiGraph GT3X+加速度计评估的PA (强度,持续时间,频率,类型).
- 还评估了传统的中国炼 (太极拳,Baduanjin);所有原因的死亡率作为主要结果;使用了Cox模型.
主要成果:
- 研究正在进行中;结果将在完成后传播.
- 分析将包括对PA测量比较的斯皮尔曼相关性.
- 考克斯的比例危险模型将评估PA-死亡率关联,对非线性效应进行限制的立方线.
结论:
- 这些发现将阐明ND-CKD患者的PA模式.
- 这项研究旨在确定改善结果的最低可取的PA水平.
- 结果将为促进ND-CKD群体体体育活动的干预措施提供信息.
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