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MAT1A激活糖解以促进NSCLC的进展取决于稳定CCND1的稳定

Shengping Shen1, Ruili Liu2, Jiazheng Huang1

  • 1Shanghai Lung Tumor Clinical Medicine Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 200030, PR China.

Cell death & disease
|October 22, 2024
PubMed
概括

甲氨基基转移酶1A (MAT1A) 在非小细胞肺癌 (NSCLC) 中被上调,通过稳定CCND1和增强糖解,促进瘤生长. 抑制MAT1A可能为NSCLC提供一种新的治疗策略.

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