静脉乳酸与儿科心脏病重症监护室系统氧和的不良相关性:试点研究
Rohit S Loomba1,2, Enrique G Villarreal3, Angela Klein2
1Division of Cardiology, Advocate Children's Hospital, Oak Lawn, IL, USA.
Cardiology in the young
|October 22, 2024
概括
在儿科心脏重症监护中,血清乳酸并不是可靠的氧气输送指标. 在这组患者中,静脉乳酸和静脉氧和没有显著的相关性,这表明乳酸不是氧气充足的良好标志物.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 关键护理医学 关键护理医学
- 新生儿生理学 新生儿生理学
背景情况:
- 心脏输出和氧气输送是儿科心脏重症监护服务提供者的关键指标.
- 热稀释和菲克原理是估计心脏输出量的常见方法.
- 中枢静脉和和乳酸盐水平用于评估心脏输出,但它们在儿科心脏重症监护中的关系尚不清楚.
研究的目的:
- 调查小儿心脏重症监护病人的静脉乳酸盐水平和静脉氧和之间的相关性.
- 为了确定乳酸是否是一个可靠的指标,该群体的氧气供应充足.
主要方法:
- 进行了一项单一中心的回顾性试点研究.
- 数据包括静脉和,心率,平均动脉血压,动脉和,大脑和脏近红外光谱和单静脉心脏状况.
- 使用贝叶斯派尔森相关性和回归分析.
主要成果:
- 总共分析了37名患者的203个数据点.
- 血清乳酸和静脉和之间没有发现显著的相关性 (相关系数 = -0.01;贝叶斯系数10 = 0.06).
- 静脉和与动脉和和脑/近红外光谱相关;回归分析确定了并行循环,动脉和脑近红外光谱作为预测因素.
结论:
- 血清乳酸盐不是评估小儿心脏重症监护病人的氧气供应充足性的可靠标志物.
- 只有当静脉和度为70%或更低时,才观察到乳酸和静脉和度之间的弱相关性.
- 需要进一步的研究来确定其他标记物来监测重症儿科患者的氧气输送.
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