对20例围产期结核病例的临床分析
Ying Zhu1, Houxi Bai1, Mingbo Zhao1
1Second Department of Infectious Disease, Kunming Children's Hospital, Kunming, 650000, Yunnan, China.
BMC infectious diseases
|October 22, 2024
概括
周产期结核病在儿童中表现为非特异性症状,使得早期诊断具有挑战性. 及时的病因调查和治疗显著改善了结果和长期发展.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 新生儿科学 新生儿科学
背景情况:
- 周产期结核病 (TB) 在婴儿中带来了诊断和治疗方面的挑战.
- 了解临床特征对于及时干预至关重要.
研究的目的:
- 分析临床表现,诊断和治疗周围结核病的儿童.
- 为儿童结核病的诊断和治疗提供临床参考.
主要方法:
- 对20例围产期结核病例的回顾性分析 (2014年2月 - 2021年9月).
- 审查流行病史,临床症状,实验室/成像数据和治疗结果.
- 包括结核素皮肤测试 (TST),干扰素释测试 (IGRAs),酸快染色和PCR.
主要成果:
- 大多数病例在症状出现3周后被诊断出来.
- 结核菌核酸聚合酶链反应 (PCR) 显示了70%的阳性.
- 胸部CT显示了各种肺部变化,巩固/atelectasis在52.6%.
结论:
- 围产结核病的临床和成像发现是不特定的.
- 对于早期诊断而言,对母亲进行彻底的检查和病因学确认至关重要.
- 及时治疗改善了预后,儿童在治疗后表现出正常的生长和发展.
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