综合饮食抗氧化剂指数和腹腔大动脉化:全国横截面研究
Zhaoxiang Wang1, Fengyan Tang1, Bo Zhao2
1Department of Endocrinology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, Jiangsu, 215300, China.
Nutrition journal
|October 22, 2024
概括
通过综合饮食抗氧化剂指数 (CDAI) 测量较高的饮食抗氧化剂摄入量,与美国成年人的腹腔大动脉化 (AAC) 风险降低有关. 这表明抗氧化剂可能会防止血管化.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 公共卫生 公共卫生
背景情况:
- 腹腔大动脉化 (AAC) 是心血管疾病风险的标志物.
- 饮食中的抗氧化剂在减轻氧化应激中发挥作用,氧化应激与动脉样硬化有关.
- 需要一个全面的饮食抗氧化剂指数来评估饮食模式的保护潜力.
研究的目的:
- 研究美国40岁及以上的成年人中综合饮食抗氧化剂指数 (CDAI) 和腹腔大动脉化 (AAC) 之间的关联.
- 为了确定更高的饮食抗氧化剂摄入量是否与较低的AAC患病率和严重程度有关.
- 探索CDAI和严重的AAC (SAAC) 之间的关系.
主要方法:
- 从2013-2014年国家健康和营养检查调查 (NHANES) 中对美国成年人 (≥40岁) 的横截面分析.
- 综合饮食抗氧化剂指数 (CDAI) 的计算基于六种饮食抗氧化剂.
- 使用AAC-24评分系统评估AAC;严重的AAC (SAAC) 被定义为AAC评分>6.
- 统计分析包括线性/逻辑回归和平滑曲线拟合来检查CDAI-AAC的关联,调整混因素.
主要成果:
- 总共有2640名参与者被分析.
- CDAI的上升水平与AAC得分和SAAC流行率的下降显著相关 (P <0.01).
- 调整后的分析显示,CDAI和AAC分数 (β = -0.083,P = 0.008) 和SAAC (OR = 0.883,P = 0.008) 之间存在显著的反向关系.
- 顺曲线的拟合证实了CDAI和AAC措施之间的负相关性.
结论:
- 饮食中抗氧化剂的摄入量,根据CDAI的量化,与腹腔大动脉化的风险相反相关.
- 更高的饮食抗氧化剂摄入量可能会保护血管化.
- 需要进一步的纵向和干预研究来证实这些发现并探索机制.
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