患有和没有COVID-19的重症监护后患者的认知恢复:差异和相似之处,一项观察性研究
Anna Gorsler1,2, Christiana Franke3, Anneke Quitschau3
1Clinic for Neurological Rehabilitation, Fachklinik Für Neurologische Frührehabilitation, Kliniken Beelitz GmbH, Paracelsusring 6a, Beelitz-Heilstätten, 14547, Brandenburg, Germany. gorsler@kliniken-beelitz.de.
Neurological research and practice
|October 23, 2024
概括
危急病患者,无论他们是否患有COVID-19,在重症监护室 (ICU) 住院后都经历了类似的认知障碍. 对于所有幸存者来说,高级认知功能的恢复是缓慢的.
科学领域:
- 神经学 神经学
- 密集护理医学 密集护理医学
- 认知科学 认知科学
背景情况:
- 重症监护病房 (ICU) 的幸存者面临高风险的后重症监护综合征 (PICS),包括认知障碍.
- 危急疾病,包括COVID-19,可能导致长期的神经系统缺陷.
研究的目的:
- 为了比较重病COVID-19幸存者与非COVID-19幸存者的急症治疗后康复过程和受影响的认知领域.
- 评估两组认知障碍严重程度和性质的差异.
主要方法:
- 在德国神经康复诊所进行的一项观察性前性研究.
- 重症患者 (COVID-19和非COVID-19,机械通风≥1周) 经历了反复的认知,精神和身体评估.
- 评估的认知功能包括信息处理速度,记忆,执行功能和单词流性.
主要成果:
- 30名患者 (每组15名) 完成了这项研究;COVID-19患者在ICU停留时间更长,并出现了更多并发症.
- 这两组在入院时都表现出类似的,显著的认知障碍,特别是在信息处理速度,单词流,灵活性和识别记忆方面.
- 在两组中,只有信息处理速度在出院后显著改善;更高阶认知功能的恢复仍然缓慢.
结论:
- 在ICU后的康复显示了幸存者的认知,精神和身体功能障碍的实质性重叠,而不论SARS-CoV-2感染.
- 进一步监测至关重要,以减轻长期负担,并促进所有ICU幸存者的功能恢复.
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