自闭症成年人的身体健康并发症风险:临床嵌套横截面研究
Megan Hunt1, Jack F G Underwood2, Leon Hubbard3
1Foundation Programme, North Bristol NHS Trust, UK; and Neuroscience & Mental Health Innovation Institute, Division for Psychological Medicine and Clinical Neuroscience, Cardiff University, UK.
BJPsych open
|October 23, 2024
概括
自闭症患者的身体健康状况比较高,包括肝病和COPD. 对于自闭症和智力障碍患者来说,这种风险甚至更大,突出了终身健康挑战.
科学领域:
- 医学研究 医学研究
- 自闭症谱系障碍研究研究
- 公共卫生 公共卫生
背景情况:
- 自闭症与身体健康状况的更高患病率有关.
- 虽然像这样的某些疾病的记录很好,但许多其他疾病缺乏足够的研究.
- 了解这些并发症对于综合护理至关重要.
研究的目的:
- 在被诊断为自闭症的个人中调查身体健康并发症的患病率.
- 将自闭症患者的健康状况与神经类型对照组进行比较.
- 检查智力障碍是否会改变自闭症和身体健康状况之间的关联.
主要方法:
- 一项嵌套的横截面研究利用了来自国家心理健康中心数据库的数据.
- 包括813名自闭症患者和2781名来自英格兰和威尔士的对照.
- 采用二项逻辑回归,控制人口和药物变量;一个亚分析包括智力残疾人.
主要成果:
- 在28种身体健康状况中,有16种在自闭症患者中明显更常见.
- 肝病,慢性肺炎,病,骨质疏松症和类风湿性关节炎的几率比率最高.
- 患有自闭症和智力障碍的个体表现出类似的模式,其中一些条件的几率甚至更高.
结论:
- 身体健康状况在自闭症患者中更为普遍.
- 某些疾病,如骨质疏松症和肝病,在具有同时出现智力障碍的人群中进一步升高.
- 研究结果强调,自闭症患者在整个成年期身体健康问题的风险增加.
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