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Updated: Jun 9, 2025

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具有改善生物成像和PCR应用性能的核酸结合 bis-acridine色剂

Olesia Kulyk1, Alexander Krivoshey1, Olga Kolosova1

  • 1Institute of Functional Materials Chemistry of State Scientific Institution "Institute for Single Crystals" of National Academy of Sciences of Ukraine, Kharkiv, 61072, Ukraine. tatarets@isc.kh.ua.

Journal of materials chemistry. B
|October 23, 2024
PubMed
概括

与EvaGreen相比,新型双烯酸色 (BAO) 染料在定量PCR (qPCR) 和DNA化曲线分析中表现优越. 这些染料为先进的生物成像和分子诊断提供了增强的DNA结合特性.

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
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