便免疫化学测试 (FIT) 基于价值的算法对症状结肠直肠患者进行分离:来自第三级护理医院的一项回顾性研究
Amal Boulbadaoui1, Ayesha Bibi2, Guleed Mohamed1
1Colorectal Surgery, University Hospitals of North Midlands National Health Service Trust, Stoke-on-Trent, GBR.
Cureus
|October 23, 2024
概括
定量便免疫化学测试 (FIT) 可以准确地诊断症状患者的结直肠癌. 这种方法有助于优先考虑紧急调查,提高医疗保健的效率,减少内镜单元的负担.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 诊断医学 诊断医学 诊断医学
背景情况:
- 结肠直肠癌 (CRC) 诊断依赖于对症状患者的及时调查.
- 便免疫化学测试 (FIT) 是一种用于检测下胃肠道出血的非侵入性查工具.
- 优化紧急结直肠检查的患者优先级对于有效的医疗保健服务至关重要.
研究的目的:
- 评估在怀疑结直肠癌的症状患者中定量FIT的诊断准确性.
- 评估FIT在优先考虑紧急结直肠检查的患者中的实用性.
- 确定FIT在管理大肠直肠诊断医疗保健资源方面的有效性.
主要方法:
- 回顾症状,FIT阳性患者转诊到结直肠诊所的回顾性审查 (2021年11月 - 2022年2月).
- 不包括18岁以下的患者.
- 基于本地算法进行的测试 (TTT) 或面对面 (F2F) 诊所的分离.
- 在各种FIT切线值下对诊断准确度,特异性和正预测值 (PPV) 的统计分析.
主要成果:
- 在915名FIT阳性患者中,9.8%被诊断为CRC.
- 较高的FIT截止值 (>100和>200微克Hb/g) 显示CRC的特异性增加 (分别为88.10%和92.27%).
- 范围所需的数量随着FIT截止值的提高而减少,这表明优先级的效率有所提高.
结论:
- 定量FIT是诊断有症状的个体结直肠癌的一个有价值的工具.
- FIT有效地帮助患者优先考虑紧急结直肠检查,优化资源配置.
- 实施定量FIT可以提高结直肠癌诊断门诊和内镜服务的效率.
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