与加拿大肠道病原体病例的抗生素处方相关的风险因素,2015-2019年
Brendan Dougherty1,2, Rita Finley3, Danielle Dumoulin2
1Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Epidemiology and infection
|October 23, 2024
概括
抗生素管理对于对抗耐药性至关重要. 这项研究发现了与肠道疾病不适当的抗生素处方相关的因素,突出了针对性干预的必要性,以优化抗生素使用.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 不适当使用抗生素是导致抗生素耐药性日益严重的问题的主要原因之一.
- 有效的抗生素管理计划需要清楚地了解当前的处方模式.
研究的目的:
- 在人类肠道疾病病例中确定与抗生素处方相关的因素.
- 为开发有针对性的抗生素管理计划提供证据.
主要方法:
- 从加拿大食品网监测系统 (2015-2019) 中分析实验室确认的肠道疾病病例.
- 实验室数据与有关人口统计,症状和抗生素处方的增强病例问卷数据的整合.
- 应用单变量和多变量逻辑回归模型来识别相关因素.
主要成果:
- 几种因素与接受肠道疾病抗生素处方有显著的关联.
- 确定的关联表明,不适当的抗生素处方做法占了显著比例.
- 特定的患者和疾病特征与抗生素处方可能性相关.
结论:
- 抗生素管理干预措施对于传染性腹至关重要,以优化抗生素的使用.
- 减少不适当的抗生素处方对于减轻抗生素耐药性至关重要.
- 对处方行为的进一步研究可以为更有效的管理策略提供信息.
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