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双边波动的感觉神经听力损失作为淋巴瘤的一种神经瘤表现
Ting-Chia Young1, Wen-Hsiu Wang1,2,3, Chia-Huei Chu4,5
1Department of Medicine, Mackay Medical College, New Taipei City, Taiwan.
The Laryngoscope
|October 23, 2024
概括
自免疫内耳疾病 (AIED) 可以导致波动性听力损失. 早期发现和治疗相关癌症,如淋巴瘤,对于管理AIED和改善结果至关重要.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 免疫学 免疫学 免疫学
- 在瘤学瘤学.
背景情况:
- 自免疫内耳疾病 (AIED) 是感官神经听力损失 (SNHL) 的不常见原因.
- 二次AIED与其他自身免疫性疾病相关,在多达30%的病例中发生.
- AIED可能是神经瘤综合征的罕见表现,最初是隐性恶性瘤.
研究的目的:
- 为了突出浮动SNHL和AIED之间的关联.
- 强调在AIED病例中考虑副瘤综合征的重要性.
- 为了呈现AIED二次扩散大B细胞淋巴瘤的病例.
主要方法:
- 一位患有双边波动性SNHL的患者的病例报告.
- 对诊断挑战和治疗反应的审查.
- 听力损失与随后的淋巴瘤诊断和治疗的相关性.
主要成果:
- 患者出现了双边波动和渐进的SNHL.
- 观察到对类固醇和免疫抑制剂治疗的部分反应.
- 听力稳定发生在成功治疗扩散大B细胞淋巴瘤后.
结论:
- 在SNHL波动的患者中应考虑AIED.
- 在AIED病例中,应调查恶性病变,特别是当自身免疫性疾病存在时.
- 及时诊断和治疗潜在疾病对于管理AIED至关重要.
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