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视觉雪综合征是不稳定的:在一个天真的人群中对VSS症状的纵向调查

Amy Claire Thompson¹, Patrick T Goodbourn¹, Jason D Forte¹

¹Melbourne School of Psychological Sciences, University of Melbourne, Parkville, Australia.

Annals of clinical and translational neurology

|October 23, 2024

概括

亚临床视觉雪综合征 (VSS) 症状可以在6周的时间内显著波动. 新的墨尔本视觉雪问卷 (MVSQ) 有效地选了一般人群中的VSS.

科学领域:

神经学神经学
眼科医生眼科眼科
临床研究临床研究

背景情况:

视觉雪综合征 (VSS) 是一种神经疾病,其特征是视觉雪,视野中的动态噪音.
亚临床VSS可能在一般人群中普遍存在,并且经常被忽视.
了解亚临床VSS进展对于全面描述VSS至关重要.

研究的目的:

为了调查亚临床视觉雪综合征 (VSS) 的性质.
开发和验证一个查工具,用于招募具有亚临床VSS症状的参与者.
评估亚临床VSS症状的时间稳定性.

主要方法:

研究1:开发和验证墨尔本视觉雪问卷 (MVSQ) 用于一般人口查.
研究1:在临床VSS.患者中评估MVSQ的面部有效性和负担.
研究2:在原始样本 (n=155) 中部署了MVSQ,在6周内重复评估以评估症状稳定性.

主要成果:

MVSQ被证明是招募具有VSS症状的个体的可行工具,表现出足够的面部有效性和低负担.
亚临床VSS症状在6周的间隔内表现出显著的变化 (科恩加权卡帕=0.56).
随着时间的推移,感知体验的影响保持稳定 (排名ICC = 0.71).

结论:

MVSQ适用于评估一般人群中与VSS相关的感知体验.
亚临床VSS症状并不完全稳定,在短时间内波动.
需要进一步的研究来确定症状波动的精确时间表,以便更好地了解VSS.

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