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探索PPARγ复发性膀癌突变体中激活过程的分子途径

Vinícius M de Oliveira1, Caique C Malospirito1, Fernando B da Silva2

  • 1Brazilian Biosciences National Laboratory, National Center for Research in Energy and Materials, LNBio/CNPEM, Campinas, SP, Brazil.

The Journal of chemical physics
|October 23, 2024
PubMed
概括

氧酶增殖器激活受体马 (PPARγ) 的特定突变增强了它的活性,促进了膀癌. I290M突变稳定了活性受体状态,提供了一个潜在的治疗点.

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