欧洲化学生物学数据库:欧洲化学生物学数据库
Ctibor Škuta1, Tomáš Müller1, Milan Voršilák1
1CZ-OPENSCREEN: National Infrastructure for Chemical Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, Prague 14220, Czech Republic.
Nucleic acids research
|October 23, 2024
概括
欧洲化学生物学数据库 (ECBD) 提供了超过430万个化学生物学查数据点的开放访问. 这个FAIR数据库通过使各种化合物选结果可查找和可重复使用来支持科学发现.
科学领域:
- 化学生物学 化学生物学
- 生物信息学是一种生物信息学.
- 药物发现 药物发现 药物发现
背景情况:
- 欧洲化学生物学数据库 (ECBD) 是EU-OPENSCREEN的中心存储库.
- 它遵循FAIR原则 (可查找性,可访问性,互操作性,可重复使用性).
- 数据根据开放访问原则提供.
研究的目的:
- 将ECBD描述为化学生物学数据的全面资源.
- 突出了ECBD的数据类型和可访问性.
- 促进在科学研究中使用ECBD数据.
主要方法:
- 欧洲央行数据库 (ECBD) 存储了初级和反选试验的阳性和阴性结果.
- 数据是使用超过107,000多种不同的化合物的库生成的.
- 测试注释通过用户支持的项目和内部努力不断丰富.
主要成果:
- 该数据库包含89个存储的数据集 (测试),其中48个可公开访问.
- 这些数据集包括大约430万个实验数据点.
- 剩余的数据将在发布禁运期长达3年后公布.
结论:
- 对于化学生物学界来说,ECBD提供了一个有价值的,符合FAIR的资源.
- 公开可访问的数据可以通过UI,API或根据CC-BY 4.0许可证的数据库倾倒来检索.
- 欧洲化学数据中心 (ECBD) 促进数据共享和加速化学生物学研究.
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