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Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

342
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
342

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前列腺特异性抗原 (PSA) 测试在一般实践中 2009-2019年

Niall Maguire1, Andrea Moloney2, Krzysztof Fic3

  • 1Bedford Medical Centre, Navan, Ireland. niall.maguire@icgp.ie.

Irish journal of medical science
|October 23, 2024
PubMed
概括

男性经常接受前列腺特异性抗原 (PSA) 测试,尽管缺乏对人口查的建议. 这种广泛的测试可能会导致在一般实践环境中过度诊断和相关的危害.

科学领域:

  • 泌尿器科 泌尿器科 泌尿器科 泌尿器科
  • 公共卫生 公共卫生
  • 临床医学 临床医学

背景情况:

  • 前列腺特异性抗原 (PSA) 测试不建议用于全人口前列腺癌查.
  • 尽管有指导方针,PSA检测仍然很普遍,导致潜在的危害,如假阳性和过度诊断.
  • 与广泛的PSA测试相关的经济成本也是一个问题.

研究的目的:

  • 在一般医疗实践中,记录患者在十年内接受PSA检测的情况.
  • 在现实临床环境中分析PSA测试的频率和结果.

主要方法:

  • 每年从临床记录中提取PSA测试的实验室结果.
  • 对所有已确诊的前列腺癌病例进行图表审查.
  • 在研究期间,分析了3313名男性的13,743个PSA结果.

主要成果:

  • 每年,18%的男性和33%的50岁以上男性接受至少一次PSA检测.
  • 第一次PSA测试在4.8%至21%的病例中超过了特定年龄的正常值.
  • 在113例发生的前列腺癌中,有84例 (74%) 通过查检测到,查检测到的病例的死亡率较低.

结论:

关键词:
一般的做法一般的做法.过度诊断是一种过度诊断前列腺癌是什么意思 前列腺癌是什么意思前列腺特异性抗原 (PSA) 是什么?查检查 查检查 查检查

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  • 在这种一般实践环境中的患者经历了PSA测试的显著暴露.
  • 有证据表明,由于广泛的PSA检测,前列腺癌的过度诊断有可能发生.