PFAS暴露与北极海鸟的精子质量较低有关
Ségolène Humann-Guilleminot1,2, Pierre Blévin3,4, Geir Wing Gabrielsen5
1Department of Environmental Science, Radboud Institute for Biological and Environmental Sciences (RIBES), Faculty of Science, Radboud University, Nijmegen 6500, the Netherlands.
Environmental science & technology
|October 23, 2024
概括
在北极海鸟中,更长链的 perfluoroalkyl carboxylates (PFCA) 与异常精子的增加有关. 其他PFAS也与压力激素相关,表明野生动物的潜在生殖损害和内分泌干扰.
科学领域:
- 环境毒理学环境毒理学
- 野生动物 生殖健康 野生动物 生殖健康
- 北极的生态系统
背景情况:
- 聚和完全化基物质 (PFAS) 是在北极野生动物中发现的持久污染物.
- 虽然研究了PFAS对鸟类生理学的影响,但它们对生殖功能,特别是精子质量的影响尚不清楚.
- 黑腿鱼 (Rissa tridactyla) 是北极生态系统健康的指标.
研究的目的:
- 为了研究血中PFAS度和黑腿猫咪的精子质量参数之间的关联.
- 检查血激素水平 (,皮质,黄素激素) 与PFAS水平和精子质量之间的关系.
- 探索PFAS在海鸟中的潜在内分泌干扰机制.
主要方法:
- 在黑腿猫的血液样本中量化PFAS度.
- 评估精子质量,包括运动能力,速度,形态和异常百分比.
- 测量了丸激素,皮质和化激素的血水平.
- 进行了相关性分析,以确定PFAS,激素和精子参数之间的关联.
主要成果:
- 在更长链的甲基碳酸盐 (PFCA;C11-C14) 和异常精子的百分比之间发现了正相关性.
- 菲奥斯林和PFNA与压力激素皮质激素呈正相关性,独立于精子异常的发现.
- 这些PFAS特有的影响突显了海鸟的潜在生殖风险.
结论:
- 较长链的PFCA可能会对海鸟的精子质量产生负面影响,这表明物质特定的生殖毒性.
- 暴露于PFAS可能与内分泌干扰有关,正如与皮质水平的相关性所表明的那样.
- 需要进一步的研究,以了解持久性污染物对野生动物生殖健康的影响.
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