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Updated: Jun 9, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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EuDockScore:用于评分蛋白质-蛋白质接口的欧几里德图神经网络

Matthew McFee1,2, Jisun Kim2, Philip M Kim1,2,3

  • 1Department of Molecular Genetics, The University of Toronto, Toronto, ON M5S 1A8, Canada.

Bioinformatics (Oxford, England)
|October 23, 2024
PubMed
概括

我们开发了新的评分功能,EuDockScore和EuDockScore-Ab,使用图形神经网络来改善蛋白质-蛋白质相互作用预测. 一个专门的模型,EuDockScore-AFM,有效地重新排列了抗体-抗原复合体的AlphaFold-Multimer的输出.

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