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Updated: Jun 9, 2025

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
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Published on: August 22, 2018

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祖先序列重建以实现阿扎菲龙的生物催化合成

Chang-Hwa Chiang1,2, Ye Wang2, Azam Hussain3

  • 1Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.

Journal of the American Chemical Society
|October 23, 2024
PubMed
概括

这项研究引入了一种新的生物信息学和祖先序列重建 (ASR) 策略,用于开发优质的生物催化酶. 这种方法加速了酶的发现和优化,使得阿扎菲隆等复杂分子的高效合成成为可能.

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